Nat Genet. 2015 Nov;47(11):1294-1303. doi: 10.1038/ng.3412. Epub 2015 Sep 28.
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
A total of 33 studies contributed genome-wide association data using self-reported ANM (age at natural (non-surgical) menopause). There was a maximum total sample size of 69,360 individuals of European descent. Studies were asked to use the full imputed set of HapMap Phase 2 autosomal SNPs and to run an additive model including top principal components and study-specific covariates.

Results file obtained from http://www.reprogen.org/Menopause_HapMap2_DayNG2015_18112015.txt.gz

Column descriptions:
MarkerName, SNP ID; allele1, effect allele; allele2, other allele; HapMap_eaf, estimated allele frequency in HapMap2; effect, effect size; stderr, standard error; p, p-value.

This ReadMe was generated by NHLBI.