A genomewide association study in the INTERVAL and UK Biobank studies, testing 29.5 million genetic variants for association with 36 red cell, white cell, and platelet traits in 173,480 European-ancestry participants. The paper describing these results was published in Cell in November 2016: Astle, William J., Elding, H., Jiang, T., et al. The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell 167, 1415-1429.e1419. Trait abbrevations: Cell Type Standard Abbreviation Long Name Unit Description Platelet PLT# Platelet count per nL Count of platelets per unit volume of blood MPV Mean platelet volume fL Mean volume of platelets PDW Platelet distribution width fL The spread of the platelet volume distribution. Note that Sysmex and Coulter use different statistics to measure spread. PCT Plateletcrit % Volume fraction of blood occupied by platelets Mature red cell RBC# Red blood cell count per pL Count of red blood cells per unit volume of blood MCV Mean corpuscular volume fL Mean volume of red blood cells HCT Hematocrit % Volume fraction of blood occupied by red cells MCH Mean corpuscular hemoglobin pg Average mass of hemoglobin per red cell MCHC Mean corpuscular hemoglobin concentration g/dL Concentration of hemoglobin with respect to unit of volume occupied by red cells HGB Hemoglobin concentration g/dL Concentration of hemoglobin with respect to unit of volume of blood RDW Red cell distribution width fL Coefficient of variation of red cell volume distribution Immature red cell RET# Reticulocyte count pL Count of reticulocytes per unit volume of blood RET% Reticulocyte fraction of red cells % Percentage of red blood cells that are reticulocytes IRF Immature fraction of reticulocytes - Fraction of reticulocytes with high RNA content, as measured by light scatter HLSR# High light scatter reticulocyte count per pL Count of high RNA content (immature) reticulocytes per unit volume of blood HLSR% High light scatter reticulocyte percentage of red cells % Immature reticulocyte count as a percentage of red blood cell count Myeloid white cell MONO# Monocyte count per nL Count of monocytes per unit volume of blood NEUT# Neutrophil count per nL Count of neutrophils per unit volume of blood EO# Eosinophil count per nL Count of eosinophils per unit volume of blood BASO# Basophil count per nL Count of basophils per unit volume of blood (NEUT+EO)# Sum neutrophil eosinophil counts per nL Aggregate count of neutrophils and eosinophils per unit volume of blood. (EO+BASO)# Sum eosinophil basophil counts per nL Aggregate count of eosinophils and basophils per unit volume of blood (BASO+NEUT)# Sum basophil neutrophil counts per nL Aggregate count of basophils and neutrophils per unit volume of blood GRAN# Granulocyte count per nL Aggregate count of granulocytes per unit volume of blood NEUT%GRAN Neutrophil percentage of granulocytes % Percentage of granulocytes that are neutrophils BASO%GRAN Basophil percentage of granulocytes % Percentage of granulocytes that are basophils EO%GRAN Eosinophil percentage of granulocytes % Percentage of granulocytes that are eosinophils MYELOID# Myeloid white cell count per nL Aggregate count of myeloid white cells GRAN%MYELOID Granulocyte percentage of myeloid white cells % Percentage of myeloid white cells that are granulocytes Lymphoid white cell LYMPH# Lymphocyte count per nL Aggregate count of lymphoid cells per unit volume of blood Compound white cell WBC# White blood cell count per nL Aggregate count of white cells per unit volume of blood MONO% Monocyte percentage of white cells % Percentage of white cells that are monocytes NEUT% Neutrophil percentage of white cells % Percentage of white cells that are neutrophils EO% Eosinophil percentage of white cells % Percentage of white cells that are eosinophils BASO% Basophil percentage of white cells % Percentage of white cells that are basophils LYMPH% Lymphocyte percentage of white cells % Percentage of white cells that are lymphocytes Each of the files has the following headers: VARIANT: Unique ID we generated for all variants in the format: “chromosome:position_reference_alternative” ID: rsID (where available) CHR: Chromosome BP: Position (GRCh37) REF: Reference allele, also our baseline allele ALT: Alternative allele, also our effect allele ALT_MINOR: Is the alternative allele also the minor allele? DIRECTION: Direction of effect EFFECT: beta (per standard deviation) SE: Standard error P: P-value MLOG10P: -log10(p-value) ALT_FREQ: Allele frequency for the alternative allele MA_FREQ: Allele frequency for the minor allele