Summary Statistics: FGL1 as a modulator of plasma D-dimer levels: exome-wide marker analysis of plasma tPA, PAI-1 and D-dimer

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Analyses were performed with the R library seqmeta on log-transformed values of D-dimer, tPA and PAI-1.
For the 3 traits, the following analyses were performed:
 - Single-SNP analyses (files prefixed with "meta_Single_")
 - Gene-based SKAT5 analyses (files prefixed with "meta_SKAT5_")
 - Gene-based T5 analyses (files prefixed with "meta_T5_")
Further, all analyses were also sex-stratified (Inter99 cohort excluded):
 - Males (files suffixed with "_M")
 - Females (files suffixed with "_F")

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Single-SNP analyses file description:

Analysis : trait analyzed
Chr : chromosome
Pos_hg19 : position (hg19 build)
dbSNPID : rsID 
Name : exomechip variant identifier
Gene : gene name
EA : effect allele
NEA : non effect allele
maf : minor allele frequency
mac : minor allele count
nmiss : number of sample missing
ntotal : number of sample in total
beta : effect
se : standard error
p : p-value
Direction : direction of effect in each individual cohort (in alphabetical order) 
nbstudy : number of studies where the variant is present

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SKAT5 analyses file description:

gene : the name of the gene or unit of aggregation being meta analyzed
p : p-value of the SKAT test
Qmeta : The SKAT Q-statistic
cmaf : The cumulative minor allele frequency
nmiss : The number of 'missing' SNPs. For a gene with a single SNP this is the number of individuals which do not contribute to the analysis, due to studies that did not report results for that SNP. For a gene with multiple SNPs, is totalled over the gene
nsnps : The number of SNPs in the gene

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T5 analyses file description:

gene : the name of the gene or unit of aggregation being meta analyzed
p : the p-value from the burden tests
beta : approximate coefficient for the effect of genotype
se : approximate standard error for the effect of genotype
cmafTotal : the cumulative minor allele frequency of the gene
cmafUsed : the cumulative minor allele frequency of snps used in the analysis
nsnpsTotal : the number of snps in the gene
nsnpsUsed : the number of snps used in the analysis
nmiss : The number of 'missing' SNPs. For a gene with a single SNP this is the number of individuals which do not contribute to the analysis, due to studies that did not report results for that SNP. For a gene with multiple SNPs, is totalled over the gene