Reference publication: PMID: 29695241 Study populations Patients with Type 1 Diabetes diagnosed before 35 years Phenotype: Coronary Arterty disease included history of myocardial infarction, revascularization, coronary artery bypass graft, Angina, CVD except stroke. Genotype: Illunina HumanCore Exome 12v1 Imputation: 1000 Genomes phase 3v5, MaCH. Association testing: mach2dat / Quicktest / Plink 1.9 Adjustment for : Age, sex, diabetic nephropathy and PCs