GIANT Consortium 2012-2015 Data File Description:
Each file consists of the following information for each SNP and its association to the specified trait based on meta-analysis in the respective publication. Significant digits for the p values, betas and standard errors are limited to two digits to further limit the possibility of identifiability.
MarkerName: The dbSNP name of the genetic marker
Allele1: The first allele (hg19 + strand). Where the regression coefficients (betas) are provided, the first allele is the effect allele. Where betas are not provided (typically the 2010 data), the first allele is the trait-increasing allele.
Allele2: The second allele (hg19 + strand)
Freq.Allele1.HapMapCEU: The allele frequency of Allele1 in the HapMap CEU population
b: beta
SE: standard error
p: p-value after meta-analysis using regression coefficients (beta and standard error), and after correction for inflation of test statistics using genomic control both at the individual study level and again after meta-analysis
N: Number of observations
GWAS Anthropometric 2015 Waist
Each trait has 6 results files:
1) Males of European ancestry
2) Males of All ancestries
3) Females of European ancestry
4) Females of All ancestries
5) Combined genders European ancestry
6) Combined genders All ancestries
If you use these Waist data please cite: Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Magi R, Strawbridge R, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JM, et al. (2015). New genetic loci link adipose and insulin biology to body fat distribution. Nature 518: 187-196.